X-ray diffraction and NMR data for the study of the location of idebenone and idebenol in model membranes

نویسندگان

  • Victoria Gómez-Murcia
  • Alejandro Torrecillas
  • Ana M. deGodos
  • Senena Corbalán-García
  • Juan C. Gómez-Fernández
چکیده

Here we present some of our data about the interaction of idebenone and idebenol with dipalmitoyl-phosphatidylcholine (DPPC). In particular, we include data of small angle X-ray diffraction (SAXD) and wide angle X-ray diffraction experiments, obtention of electronic profiles of the membranes, (2)H-NMR and (31)P-NMR, as part of the research article: "Both idebenone and idebenol are localized near the lipid-water interface of the membrane and increase its fluidity" (Gomez-Murcia et al., 2016) [1]. These data were obtained from model membranes that included different proportions of idebenone and idebenol, at temperatures both above and below of the gel to fluid phase. The X-ray experiments were carried out by using a modified Kratky compact camera (MBraun-Graz-Optical Systems, Graz Austria), incorporating two coupled linear position sensitive detectors. The NMR data were collected from a a Bruker Avance 600 instrument.

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عنوان ژورنال:

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2016